BV-FAPESP: research projects supported in this center
ARIES Project In the Media: news about the Center
Antimicrobial resistance (AMR) has been considered one of the main threats to the human race in the 21st century. An example of rapid and unstoppable Darwinian adaptation through natural selection is underway, in which microorganisms are constantly evolving to survive antimicrobials. In this fight, microorganisms have advantages unless effective approaches to control and prevent the spread of AMR are developed.
In this project, the creation of the São Paulo Institute of Antimicrobial Resistance of São Paulo (ARIES) is proposed, which will bring together researchers from 5 universities in São Paulo state with specialists from public agencies (EMBRAPA, CETESB) and representatives of the Ministry of Agriculture, Livestock and Supply (MAPA), the Ministry of Health and the National Health Surveillance Agency (ANVISA), and the Pan American Health Organization (PAHO). This ambitious and pioneering project has as its convergent objective the confrontation of AMR through concepts of Global Health and One Health. Mitigating the threat of AMR requires a multidisciplinary approach that recognizes and interferes with the causes of AMR at the human-animal-environment interface.
ARIES will have five main pillars to achieve our main objectives: 1) Socio-Environmental Observatory and Data Science Center: surveillance of the ecosystems involved in the emergence and dissemination of AMR; 2) Characterization of microbial evolution, AMR mechanisms, adaptation and pathogenicity of microorganisms; 3) Development and validation of new strategies for the control and prevention of AMR in humans, animals and the environment; 4) ARIES as a Center for Innovation and Entrepreneurship and an Advanced Center in AMR aiming at knowledge transfer and public policies; and 5) Diffusion of ARIES – Knowledge in connection with Society, Education and Dissemination.
ARIES will not only contribute to the development of a more sophisticated and comprehensive surveillance system, capable of early detection of the emergence of AMR in the context of One Health, but will also generate new strategies to respond to, contain and prevent resistant infections in health institutions, food production and the community.
2023-07-12
A study conducted at the Federal University of São Paulo shows that 20% of patients with bloodstream infections are not treated, and at least half of those treated die. Diagnostic techniques must improve, the authors warn.
2023-04-12
The new RIDCs will conduct research on biodiversity and climate change, antimicrobial resistance, the biology of bacteria and bacteriophages, theranostic medicine against cancer, and tropical agriculture’s carbon footprint.
