BV-FAPESP: research projects supported in this Center
CeTICS in the Media: news about the Center
The Center for Research on Toxins, Immune-Response and Cell Signaling (CeTICS) mission is to probe into the biological systemic response of cells, tissues, or whole organisms using chemically defined peptide toxins as molecular tools.
The objective is to discover and chemically characterize molecular targets of toxins, which very likely initiate biological responses of interest in human pathophysiology and therapeutics. These molecular targets are critical receptors and/or other mediators, which trigger downstream molecular signaling networks underlying biological homeostatic functions.
A research group at Butantan Institute performed tests on animal models with asthma as a reference and demonstrated that the peptide from Thalassophryne nattereri, common in North and Northeast Brazil, is safe and efficacious.