A study led by Brazilian researchers suggests that the mechanism that exacerbates dengue infection following a case of zika differs from that acting on second-time dengue patients. The finding is relevant to the development of a zika vaccine.
Human Genome and Stem-Cell Research Center
A study conducted at a FAPESP-supported research center discovered a link between the protein VAPB and tumor cell proliferation in medulloblastoma, one of the most common and aggressive brain tumors in children.
Considered an invasive species, Sus scrofa causes damage to farmers in an important part of Brazil’s savanna-like biome. The researchers analyzed 55 landscapes in São Paulo state, observing larger numbers of native mammals in areas with well-conserved vegetation and diversified crops, while native species richness was far lower in areas of monoculture.
With the new contributions from abroad, the Scientific Expeditions call, issued in partnership with the National Council for Scientific and Technological Development, now has a fund totaling some BRL 94 million.
CD4+ T cells play an important role in the immune response to pulmonary infections, but excessive amounts can damage the lungs. In experiments with mice, researchers at the University of São Paulo discovered what leads to this exacerbated response.
The startup has been supported by FAPESP since its foundation in 2020. The device can be used to make film for perovskite solar cells, biomaterials for wound dressings and tissue regeneration, and novel drug and cosmetic delivery systems.
Data from the Phase 3 clinical trial was published on February 1st in The New England Journal of Medicine. The vaccine is safe for both participants who have had dengue and those who have never been exposed to the virus before.
This part of the seafloor in the South Atlantic is rich in cobalt, nickel and lithium, as well as tellurium and other rare earths critical to the energy transition. The scientists plan to continue research on its natural processes as a contribution to prospecting efforts.
Developed by a team of Brazilian researchers, the device is made of plant-based material with little environmental impact, and detects pesticides in a few minutes, helping to certify food safety.
André Morandini, Director of the University of São Paulo’s Center for Marine Biology, was on the team that has published a description of a rare medusa found at a depth of 812 meters. The animal has been sighted only twice in a deep-sea volcanic structure called Sumisu Caldera, in the Ogasawara Islands.
In 18 cities of the Barretos region, where the proportion of Black people in the population is smaller, cancer kills more members of this ethnic group, whereas in the capital of the same state, it kills more White people, according to a study that compares cancer mortality rates and points to ways of reducing inequalities in diagnosis and treatment.
In experiments with rats, researchers at São Paulo State University detected changes in the expression of more than 700 genes in offspring. One of these genes is known to be associated with prostate cancer.
The material is a compound similar to clay and enables inspectors to carry out in-situ assessment of structural conditions in buildings, bridges, dams and other structures without having to drill for samples and analyze them in a laboratory.
The two parties are interested in collaborative research on sustainable use of biodiversity in the Amazon, prevention of transmissible and chronic diseases, and sustainable construction, among other subjects.
Some species of cetacean are up to 4 meters in length, while others reach 30 meters. According to researchers at the State University of Campinas, genes that favor the colossal growth of these mammals also inhibit the development of cancer.
A study involving 20 women with rheumatoid arthritis and high blood pressure demonstrates the benefits of walking at moderate speed for 30 minutes even after tests that simulate stressful situations and tend to raise blood pressure.
