Obesity and Comorbidities Research Center
In experiments with mice, researchers at the State University of Campinas observed alterations in feed consumption, weight gain, anxious behavior and an increase in central nervous system, adipose tissue and liver inflammation.
Optics and Photonics Research Center
Photodynamic therapy developed by the Center for Research in Optics and Photonics, which is supported by FAPESP, has been recommended by Brazil’s federal body responsible for including novel healthcare technologies in the national health service.
Center for Research and Development of Functional Materials
One of the goals of the study conducted by scientists at the Center for Development of Functional Materials and the Center for Innovation on New Energies is to reduce atmospheric emissions of this greenhouse gas.
Center for Research and Innovation in Biodiversity and Drug Discovery
Similar programs and FAPESP’s pragmatism arouse interest in intensifying collaboration and joint calls for proposals involving research centers in Switzerland and São Paulo.
Center for Research on Inflammatory Diseases
A team affiliated with a FAPESP-supported research center showed in mice that molecules capable of preventing the peptide C5a from binding to its cellular receptor helped prevent lung damage and other complications typical of severe COVID-19.
Center for Research on Inflammatory Diseases
A study conducted at the University of São Paulo and reported in PNAS explains hyperglycemia in hospitalized patients and shows how SARS-CoV-2 causes symptoms similar to those of diabetes.
Center for Research on Redox Processes in Biomedicine
Researchers at the University of São Paulo observed the effects of adiponectin in trials involving blood samples from lean and obese subjects. The discovery points to novel routes to treatment for type 2 diabetes and related dysfunctions.
Antimicrobial Resistance Institute of São Paulo (Aries Project)
A study conducted at the Federal University of São Paulo shows that 20% of patients with bloodstream infections are not treated, and at least half of those treated die. Diagnostic techniques must improve, the authors warn.
Brazilian Research Institute for Neuroscience and Neurotechnology
Brazilian researchers analyzed data from MRI scans and various tests to detect biological alterations linked to the neurological symptoms most reported by patients, especially anxiety, depression, sleepiness and fatigue. The latest results were presented to the ninth edition of BRAINN Congress.
Center for Research, Teaching, and Innovation in Glass
The technique was developed at the Federal University of São Carlos (UFSCar) in São Paulo state, Brazil, and could impact the manufacturing of batteries, smartphone screens and other devices.
Center for Research on Toxins, Immune-Response and Cell Signaling
A research group at Butantan Institute performed tests on animal models with asthma as a reference and demonstrated that the peptide from Thalassophryne nattereri, common in North and Northeast Brazil, is safe and efficacious.
Center for Research on Inflammatory Diseases
Leishmania alters the structure of the human protein that would normally induce the death of infected cells and weakens the inflammatory response. Reported in Nature Communications, the discovery could serve as a basis for better treatment.
Center for Research and Innovation in Biodiversity and Drug Discovery
In vitro experiments were conducted at a FAPESP-supported research center with a synthetic peptide inspired by molecules secreted by the probiotic bacterium Lactobacillus plantarum.
Food Research Center
Scientists at a FAPESP-supported research center combined substances extracted from fruit residues and egg white to package nanoparticles of anthocyanin, a plant pigment with antioxidant action. This nanoencapsulation prevents breakdown of the molecule and lets a larger amount reach the gut, where it is absorbed.
Center for Research and Development of Functional Materials
The novel material was synthesized at the Center for Development of Functional Materials. The aim of the study was to combat the contamination caused by inappropriate disposal of pesticides and pharmaceuticals.
Center for Research on Inflammatory Diseases
Scientists who analyzed the combined use of two drugs – paclitaxel and immune checkpoint inhibitors – made discoveries that could pave the way for future research to combat the pain caused by other diseases.
Center for Research and Development of Functional Materials
A company funded by FAPESP’s program to support innovation by small businesses is launching a dietary supplement for consumer hair care.
Center for Computational Engineering and Sciences
A study conducted at the State University of Campinas integrated knowledge in several fields with high-performance computing to investigate the properties of water inferred to exist in large quantities deep inside the ice giants.
