Center for Research on Inflammatory Diseases
In an article published in the Journal of Experimental Medicine, a group affiliated with a FAPESP-supported research center reports that an enzyme associated with energy production in cells also participates in the differentiation of immune cells involved in exacerbated inflammation. The discovery could lead to more effective treatment.
Research, Innovation and Dissemination Center for Neuromathematics
Study by Brazilian and South African researchers is the first to prove, using a graph analysis tool, that REM dream narratives tend to be more complex and connected than reports of non-REM dreams
Obesity and Comorbidities Research Center
Led by research groups from the universities of Campinas and São Paulo, the investigation combined MRI scans of mild COVID-19 patients, analysis of brain tissue samples from patients who died from COVID-19, and experiments performed with human nerve cells infected in the laboratory.
Center for Metropolitan Studies
An article in The Lancet stresses the vulnerability of these health workers, whose readiness to counter fake news with trustworthy information, and to monitor COVID-19 patients in home isolation, has been neglected.
Researchers affiliated with institutions in Brazil and elsewhere analyzed blood work from almost 179,000 people who were tested for the novel coronavirus. They obtained the data from COVID-19 Data Sharing/BR, an open-access repository established by FAPESP.
Center for Research on Inflammatory Diseases
The study by more than 30 Brazilian scientists investigated tens of thousands of genomic, transcriptomic and proteomic variables, discovering several alterations caused by the virus.
Human Genome and Stem-Cell Research Center
A study is being conducted by a research center supported by FAPESP to determine whether people who develop severe forms of the disease have risk genes and whether asymptomatic people or patients with only mild symptoms have protective genes.
Center for Research on Inflammatory Diseases
Benefits were observed in a clinical trial involving 38 volunteers treated at the teaching hospital of the University of São Paulo’s Ribeirão Preto Medical School. The drug is cheap and can shorten ICU stays but should not be used outside hospitals, the researchers warn.
Center for Research on Inflammatory Diseases
Researchers have correlated information on drugs, genes and diseases to identify potential candidates for psychiatric and neurological treatment. The methodology they developed will be used to search for drugs against COVID-19.
Research, Innovation and Dissemination Center for Neuromathematics
Brazilian researchers showed that the degree of suffering caused by the pandemic and social isolation can be measured by interpreting dream narratives with the aid of speech analysis tools.
Center for Research in Mathematical Sciences Applied to Industry
The reduction resulting from implementation of these measures in São Paulo has been calculated for the period between mid-March and early May using a mathematical model developed by a FAPESP-funded research center. The scientists also estimated that these two public health measures reduced the peak of transmission by 25% in Brasília.
Center for Research and Development of Functional Materials
In laboratory tests, the material inactivated 99.9% of SARS-CoV-2 in two minutes. The technology developed by the startup, which is supported by FAPESP, will be used to produce face masks and hospital apparel.
Center for Research in Mathematical Sciences Applied to Industry
The open-access tool was developed in Brazil by researchers at the Center for Mathematical Sciences Applied to Industry to minimize the risk of shortages and overspending.
Center for Research and Innovation in Biodiversity and Drug Discovery
Synthetic compounds and molecules derived from natural products belonging to Brazil’s biodiversity are being screened by teams at the Center for Innovation in Biodiversity and Drug Discovery, which is supported by FAPESP.
Center for Research on Inflammatory Diseases
Study conducted by the FAPESP-funded Center for Research on Inflammatory Diseases (CRID) shows that drug currently used to treat cystic fibrosis can help prevent complications from infection by SARS-CoV-2.
Obesity and Comorbidities Research Center
Brazilian researchers are the only Latin American group to have had a project selected in an international request for applications by the Chan Zuckerberg Initiative. Funding of more USD 175,000 has been awarded to the study, which will be the first in Brazil to use single-cell analysis.
Brazilian Research Institute for Neuroscience and Neurotechnology
Based on quantitative MRI, researchers measured cortical volume in 51,665 participants and correlated the data with genetic markers.
Center for Metropolitan Studies
Only 13.8% of the workforce has jobs in sectors not badly hit by social isolation according to a research network set up to propose ways of improving the quality of government policies for dealing with the crisis.
Center for Research on Inflammatory Diseases
Scientists affiliated with a research center supported by FAPESP set out to understand the strategies used by immune cells to combat the most severe phase of the disease.
