Patient’s own cells are used in innovative treatment for cancer

Center for Cell-Based Therapy

Patient with advanced refractory lymphoma was treated in Brazil by researchers at a center funded by FAPESP. The technique known as CAR T-cell therapy was used for first time ever in Latin America.

Novel material with strong action against fungi and tumors

Center for Research and Development of Functional Materials

Researchers at a Research, Innovation and Dissemination Center supported by FAPESP have created a composite with antifungal properties that are 32 times greater than those of silver by irradiating a metallic tungstate with electrons and femtosecond laser light.

New species of parasite is identified in fatal case of visceral leishmaniasis

Center for Research on Inflammatory Diseases

Phylogenomic analysis shows that pathogen isolated in Brazilian hospital does not belong to the genus Leishmania. Researchers are investigating whether this species alone can cause severe disease or intensifies symptoms in co-infected patients.

Researchers discover a link between two important products of nitric oxide

Center for Research on Redox Processes in Biomedicine

Oxide plays a key role in cardiovascular and neurodegenerative diseases as well as cancer. Experiments reveal a hitherto unknown mechanism underlying the formation of nitroso thiols.

Acute chikungunya infection studied at the molecular level in Brazilian patients

Center for Research on Inflammatory Diseases

Using a systems biology approach, Brazilian researchers identified several genes that can be explored as therapeutic targets and as biomarkers of predisposition to chronic joint pain.

New mechanisms that regulate pluripotency in embryonic stem cells are discovered

Center for Cell-Based Therapy

A study by researchers at the Center for Cell-Based Therapy, which is supported by FAPESP, identified microRNAs involved in pluripotency maintenance and cell differentiation. The discovery paves the way to the development of drugs capable of making ESCs regress to the earliest stage of development.

New model facilitates the prediction of crystallization in glass particles

Center for Research, Teaching, and Innovation in Glass

A study by researchers affiliated with a research center supported by FAPESP can help scientists develop new glass and glass-ceramic materials and predict glass stability during use.

Bioactive material is produced by 3D printing

Center for Research, Teaching, and Innovation in Glass

Research center supported by FAPESP simplifies and cheapens the fabrication of glass-ceramic material that can be used in ocular prosthetics and dentin hypersensitivity treatment, among other applications.

A mechanism that makes infants more likely than adults to die from sepsis is discovered

Center for Research on Inflammatory Diseases

Scientists at the Center for Research on Inflammatory Diseases (CRID) show why pediatric patients with sepsis suffer from more inflammation and organ injury than adults. New treatment strategies may be tested.

Shape influences the properties of nanomaterials

Center for Research and Development of Functional Materials

Researchers at the Center for Development of Functional Materials developed a method to identify the ideal shape of nanoparticles with specific properties or characteristics.

Sensor detects carbon monoxide to avoid cases of CO poisoning

Center for Research and Development of Functional Materials

Use of a device created by the FAPESP-funded Center for Development of Functional Materials, could be made compulsory in Argentina, where 250 deaths from CO poisoning are reported each year.

Innovative packaging may soon be mass-producible

Food Research Center

Scientists affiliated with the Food Research Center in Brazil are working to improve industrial feasibility of disruptive technologies such as the packaging that warns costumers when food starts spoiling.

Freshwater stingray venom varies according to sex and age

Center for Research on Toxins, Immune-Response and Cell Signaling

A study by the FAPESP-funded Research, Innovation and Dissemination Center shows that toxins produced by young female stingrays cause more pain, whereas toxins produced by adult stingrays cause tissue necrosis.

Applications open for School of Advanced Science on the Molecular Basis of Inflammatory Diseases

Center for Research on Inflammatory Diseases

Graduate students and researchers from any country have until June 23 to apply for this event, which is supported by FAPESP and will take place at the University of São Paulo’s Ribeirão Preto Medical School in Brazil.

Devices help predict seizures and treat patients with epilepsy

Brazilian Research Institute for Neuroscience and Neurotechnology

Implantable devices which could improve the quality of patients’ lives – Australian-made and still under tests – were presented to the congress of BRAINN, a FAPESP-funded Research, Innovation and Dissemination Center.

Enzyme may indicate predisposition to cardiovascular disease

Center for Research on Redox Processes in Biomedicine

Study suggests that people with low levels of PDIA1 in blood plasma may be at high risk of thrombosis; this group also investigated PDIA1’s specific interactions in cancer.

Biochemical compound responsible for blood pressure drop in sepsis is discovered

Center for Research on Redox Processes in Biomedicine

International research group demonstrates the involvement of singlet molecular oxygen in vasodilation, causing a sharp decline in blood pressure in severe inflammatory processes such as sepsis.

Innovative technology to treat skin cancer awaits approval by Brazil’s national health service

Optics and Photonics Research Center

The Center for Research in Optics and Photonics, supported by FAPESP, has developed a device for the noninvasive treatment of nonmelanoma skin cancer, the most frequent type worldwide.